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"Observation of intestinal movement in rabbits were performed through use of an abdominal window in peritoneal dialysis. The causes of an adequate drainage were also observed, through the abdominal window, and better drainage was obtained as a result of clear vision and catheter adjustment. Generally it was observed that the amount of small intestinal movement diminishes after dialysis solution was introduced into the peritoneal cavity, and the larger the amount of solution, the slower the small intestinal movement. The smaller dosage is better for effecting a diminished intestinal movement; however, the effect of the dialysis is not so great, because all the surface of the peritoneum can not be used. On the other hand, the larger dosage brings on a slowing down of the intestinal movement; yet its effect on the peritoneal dialysis is greater. Our observation lead us to conclude that 200cc of solution is more popular for rabbit experiment and that dosage above this should be avoided. Less influence to the small intestinal movement was noticed when the temperature of the solution remained a little higher than body temperature. The nephrectomized rabbits and the anuric rabbits show less intestinal movement than the normal rabbits. The possible causes of ilus and abdominal distension in peritoneal dialysis were noted and discussed. After giving prostigmin in dialysate the frequency of intestinal movement increased almost to normal. Judging from the result of this experiment, it is advisable to use small doses of prostigmin in dialysate routinely in peritoneal dialysis."
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